When’s the Perfect Time to Get a Flu Shot?

When’s the Perfect Time to Get a Flu Shot?
When’s the Perfect Time to Get a Flu Shot?

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For about 60 years, health authorities in the United States have been championing a routine for at least some sector of the public: a yearly flu shot. That recommendation now applies to every American over the age of six months, and for many of us, flu vaccines have become a fixture of fall.

The logic of that timeline seems solid enough. A shot in the autumn preps the body for each winter’s circulating viral strains. But years into researching flu immunity, experts have yet to reach a consensus on the optimal time to receive the vaccine—or even the number of injections that should be doled out.

Each year, a new flu shot recipe debuts in the U.S. sometime around July or August, and according to the CDC the best time for most people to show up for an injection is about now: preferably no sooner than September, ideally no later than the end of October. Many health-care systems require their employees to get the shot in this time frame as well. But those who opt to follow the CDC current guidelines, as I recently did, then mention that fact in a forum frequented by a bunch of experts, as I also recently did, might rapidly hear that they’ve made a terrible, terrible choice.

“There’s no way I would do what you did,” one virologist texted me. “It’s poor advice to get the flu vaccine now.” Florian Krammer, a virologist at Mount Sinai’s Icahn School of Medicine, echoed that sentiment in a tweet: “I think it is too early to get a flu shot.” When I prodded other experts to share their scheduling preferences, I found that some are September shooters, but others won’t juice up till December or later. One vaccinologist I spoke with goes totally avant-garde, and nabs multiple doses a year.

There is definitely such a thing as getting a flu shot too early, as Helen Branswell has reported for Stat. After people get their vaccine, levels of antibodies rocket up, buoying protection against both infection and disease. But after only weeks, the number of those molecules begins to steadily tick downward, raising people’s risk of developing a symptomatic case of flu by about 6 to 18 percent, various studies have found. On average, people can expect that a good portion of their anti-flu antibodies “are meaningfully gone by about three or so months” after a shot, says Lauren Rodda, an immunologist at the University of Washington.

That decline is why some researchers, Krammer among them, think that September and even October shots could be premature, especially if flu activity peaks well after winter begins. In about three-quarters of the flu seasons from 1982 to 2020, the virus didn’t hit its apex until January or later. Krammer, for one, told me that he usually waits until at least late November to dose up. Stanley Plotkin, a 90-year-old vaccinologist and vaccine consultant, has a different solution. People in his age group—over 65—don’t respond as well to vaccines in general, and seem to lose protection more rapidly. So for the past several years, Plotkin has doubled up on flu shots, getting one sometime before Halloween and another in January, to ensure he’s chock-full of antibodies throughout the entire risky, wintry stretch. “The higher the titers,” or antibody levels, Plotkin told me, “the better the efficacy, so I’m trying to take advantage of that.” (He made clear to me that he wasn’t “making recommendations for the rest of the world”—just “playing the odds” given his age.)

Data on doubling up is quite sparse. But Ben Cowling, an epidemiologist and flu researcher at Hong Kong University, has been running a years-long study to figure out whether offering two vaccines a year, separated by roughly six months, could keep vulnerable people safe for longer. His target population is Hong Kongers, who often experience multiple annual flu peaks, one seeded by the Northern Hemisphere’s winter wave and another by the Southern Hemisphere’s. So far, “getting that second dose seems to give you additional protection,” Cowling told me, “and it seems like there’s no harm of getting vaccinated twice a year,” apart from the financial and logistical cost of a double rollout.

In the U.S., though, flu season is usually synonymous with winter. And the closer together two shots are given, the more blunted the effects of the second injection might be: People who are already bustling with antibodies may obliterate a second shot’s contents before the vaccine has a chance to teach immune cells anything new. That might be why several studies that have looked at double-dosing flu shots within weeks of each other “showed no benefit” in older people and certain immunocompromised groups, Poland told me. (One exception? Organ transplant recipients. Kids getting their very first flu shot are also supposed to get two of them, four weeks apart.)

Even at the three-ish-month mark past vaccination, the body’s anti-flu defenses don’t reset to zero, Rodda told me. Shots shore up B cells and T cells, which can survive for many months or years in various anatomical nooks and crannies. Those arsenals are especially hefty in people who have banked a lifetime of exposures to flu viruses and vaccines, and they can guard people against severe disease, hospitalization, and death, even after an antibody surge has faded. A recent study found that vaccine protection against flu hospitalizations ebbed by less than 10 percent a month after people got their shot, though the rates among adults older than 65 were a smidge higher. Still other numbers barely noted any changes in post-vaccine safeguards against symptomatic flu cases of a range of severities, at least within the first few months. “I do think the best protection is within three months of vaccination,” Cowling told me. “But there’s still a good amount by six.”

For some young, healthy adults, a decent number of flu antibodies may actually stick around for more than a year. “You can test my blood right now,” Rodda told me. “I haven’t gotten vaccinated just yet this year, and I have detectable titers.” Ali Ellebedy, an immunologist at Washington University in St. Louis, told me he has found that some people who have regularly received flu vaccines have almost no antibody bump when they get a fresh shot: Their blood is already hopping with the molecules. Preexisting immunity also seems to be a big reason that nasal-spray-based flu vaccines don’t work terribly well in adults, whose airways have hosted far more flu viruses than children’s.

Getting a second flu shot in a single season is pretty unlikely to hurt. But Ellebedy compares it to taking out a second insurance policy on a car that’s rarely driven: likely of quite marginal benefit for most people. Plus, because it’s not a sanctioned flu-vaccine regimen, pharmacists might be reluctant to acquiesce, Poland pointed out. Double-dosing probably wouldn’t stand much of a chance as an official CDC recommendation, either. “We do a bad enough job,” Poland said, getting Americans to take even one dose a year.

That’s why the push to vaccinate in late summer and early fall is so essential for the single shot we currently have, says Huong McLean, a vaccine researcher at the Marshfield Clinic Research Institute in Wisconsin. “People get busy, and health systems are making sure that most people can get protected before the season starts,” she told me. Ellebedy, who’s usually a September vaccinator, told me he “doesn’t see the point of delaying vaccination for fear of having a lower antibody level in February.” Flu seasons are unpredictable, with some starting as early as October, and the viruses aren’t usually keen on giving their hosts a heads-up. That makes dillydallying a risk: Put the shot off till November or December, and “you might get infected in between,” Ellebedy said—or simply forget to make an appointment at all, especially as the holidays draw near.

In the future, improvements to flu-shot tech could help cleave off some of the ambiguity. Higher doses of vaccine, which are given to older people, could rile up the immune system to a greater degree; the same could be true for more provocative vaccines, made with ingredients called adjuvants that trip more of the body’s defensive sensors. Injections such as those seem to “maintain higher antibody titers year-round,” says Sophie Valkenburg, an immunologist at Hong Kong University and the University of Melbourne—a trend that Ellebedy attributes to the body investing more resources in training its fighters against what it perceives to be a larger threat. Such a switch would likely come with a cost, though, McLean said: Higher doses and adjuvants “also mean more adverse events, more reactions to the vaccine.”

For now, the only obvious choice, Rodda told me, is to “definitely get vaccinated this year.” After the past two flu seasons, one essentially absent and one super light, and with flu-vaccination rates still lackluster, Americans are more likely than not in immunity deficit. Flu-vaccination rates have also ticked downward since the coronavirus pandemic began, which means there may be an argument for erring on the early side this season, if only to ensure that people reinforce their defenses against severe disease, Rodda said. Plus, Australia’s recent flu season, often a bellwether for ours, arrived ahead of schedule.

Even so, people who vaccinate too early could end up sicker in late winter—in the same way that people who vaccinate too late could end up sicker now. Plotkin told me that staying apprised of the epidemiology helps: “If I heard influenza outbreaks were starting to occur now, I would go and get my first dose.” But timing remains a gamble, subject to the virus’s whims. Flu is ornery and unpredictable, and often unwilling to be forecasted at all.

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New robotic arm at the Kolling Institute to drive joint replacement in Australia

New robotic arm at the Kolling Institute to drive joint replacement in Australia
New robotic arm at the Kolling Institute to drive joint replacement in Australia

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A new robotic arm at the Kolling Institute, a joint venture between the Northern Sydney Local Health District and the University of Sydney, is seen to improve hip and knee replacements in Australia.

WHAT IT DOES

Called KOBRA (Kolling Orthopaedic Biomechanics Robotic Arm), the orthopaedic biomechanics robot is one of the only two robots in the country that is based on simVitro –  a hardware neutral joint testing system that came out of the Cleveland Clinic’s Lerner Research Institute.

The robot simulates complex human movements on joints to provide researchers with a “clearer picture” of how joints will perform in various situations, explained Elizabeth Clarke, associate professor at the University of Sydney and the director of the Kolling Institute’s Murray Maxwell Biomechanics Laboratory. 

It can test complex movements and activities that involve compression and twisting like hip flexing, squatting, walking and throwing.

KOBRA’s development was backed by the NSW Investment Boosting Business Innovation program and the Royal North Shore Hospital Staff Specialist Trust Fund. 

WHY IT MATTERS

Based on a media release, KOBRA is expected to be used to test implants, particularly for hip and knee replacements, to gauge how the implants will work. It will also be used to help validate computer models that assist surgeons in the placement of implants. Additionally, the robot will be likely used to assist surgeons working to repair chronic shoulder instability. 

Moreover, researchers are seeking to apply the information and data provided by KOBRA across disciplines, extending research capabilities and leading to new surgical techniques.

MARKET SNAPSHOT

Just last year, Smith+Nephew, a British medtech company, launched in Australia and New Zealand its handheld robotics solution for unicompartmental and total knee arthroplasties. The US FDA-approved CORI Surgical System is said to be ideal for ambulatory surgery centres and outpatient surgery.

ON THE RECORD

“It is a very exciting time for musculoskeletal research and surgery and it’s tremendously encouraging to see this world-leading technology coming to the Kolling Institute. It will assist researchers, engineers and surgeons, and ultimately lead to improved surgical techniques, better physical function and good long-term health outcomes for our community,” commented Bill Walter, professor of Orthopaedics and Traumatic Surgery at the University of Sydney and an orthopaedic surgeon at the Royal North Shore Hospital.

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AI firm TIIM Healthcare gets exclusive IP for Duke-NUS sepsis triaging tech

AI firm TIIM Healthcare gets exclusive IP for Duke-NUS sepsis triaging tech
AI firm TIIM Healthcare gets exclusive IP for Duke-NUS sepsis triaging tech

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TIIM Healthcare, an AI health technology company in Singapore, has received an exclusive IP license to commercialise a novel technology developed by the Duke-NUS Medical School to identify patients at risk of dying from sepsis.

Established in 2016, TIIM, which stands for Technology Innovation in Medicine, develops AI triaging solutions. Its flagship product, aiTRIAGE, incorporates both heart rate variability and common vital signs to identify patients who are at risk of major adverse cardiac events.

WHAT IT’S ABOUT

The Duke-NUS technology adopts a novel scoring system, which also uses HRV, HRnV, vital signs and quick sequential organ failure assessment to predict in-hospital mortality among sepsis patients in the emergency ward. The solution does not require blood tests and it can deliver risk assessment results within 10 minutes – making it possible to be used for continuous monitoring of mortality risk among warded sepsis patients. 

The technology was developed using data obtained from about 340 sepsis patients at Singapore General Hospital’s emergency department. Based on a study published last year in the peer-reviewed journal PLOS One, its predictive model outperformed existing sepsis risk scoring models.

WHY IT MATTERS

Every year, sepsis affects over 50 million people worldwide, resulting in about five million deaths in both adult and child populations. In Singapore, sepsis from pneumonia and urinary tract infection claimed nearly 5,000 deaths in 2019 alone. 

Currently, conducting a blood test is the most accurate way to assess a patient’s mortality risk from sepsis. However, results may take two to four hours, which could delay the delivery of appropriate treatment. 

“Early risk stratification in septic patients using a quick and efficient triage tool would have great value in the emergency department,” said Professor Marcus Ong, director of the Health Services & Systems Research Programme at Duke-NUS Medical School and the senior author of the study. Using the novel sepsis triaging tech, EDs can efficiently redirect limited but necessary hospital resources to prevent high-risk patients from going into septic shock.

Meanwhile, TIIM Healthcare plans to integrate the novel technology into its platform to also help augment the accuracy and analytical capabilities of clinicians to triage septic patients. 

MARKET SNAPSHOT

In Australia, AI has also been applied to develop a tool that can quickly assess the severity and mortality risk of patients with sepsis. Developed by eHealth NSW, the AI-powered sepsis risk tool was trained using historic patient data to provide a risk score to septic patients. Most recently, the Westmead Hospital started to pilot the technology in its ED waiting rooms.

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How state abortion bans complicate telehealth abortions : Shots

How state abortion bans complicate telehealth abortions : Shots
How state abortion bans complicate telehealth abortions : Shots

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Allison Case is a family medicine physician who is licensed to practice in both Indiana and New Mexico. Via telehealth appointments, she’s used her dual license in the past to help some women who have driven from Texas to New Mexico, where abortion is legal, to get their prescription for abortion medication. Then came Indiana’s abortion ban.

Farah Yousry/ Side Effects Public Media


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Farah Yousry/ Side Effects Public Media

Allison Case, a family medicine physician, spends much of her time working in a hospital where she delivers babies and provides reproductive health care services, including abortions.

Case lives and works in Indiana, where a ban on most abortions took effect for a week in late September until a judge temporarily halted the ban — a stay the state is certain to appeal. Case is also licensed to practice in New Mexico, a state where abortion remains legal.

Before Indiana’s abortion ban took effect, Case would use her days off to provide reproductive health services, including abortion care, via telemedicine through a clinic that serves patients in New Mexico. Many of them travel from neighboring Texas, where abortion is banned.

Some travel solo, she says, and others have their children with them.

“Some people are [staying in] hotels, others might have family or friends they can stay with, some are just sleeping in their cars,” Case says. “It’s really awful.”

During a telemedicine appointment, doctors, nurses or other qualified health professionals review the medical history of the patient and ensure eligibility for a medication abortion. They give the patient information about how the two pills work, how to take them, what to look out for as the body expels the pregnancy, and when to seek medical attention in the rare instance of complications. The medications are then mailed to the patient, who must provide a mailing address in a state where abortion is legal.

In the U.S., more than a dozen states severely restrict access to abortion, and almost as many have such laws in the works. Across the country, since Roe v. Wade was overturned, clinics that do provide abortions have seen an increase in demand. Many clinics rely on help from physicians out of state, like Case, who are able to alleviate some of the pressure and keep wait times down by providing services via telemedicine.

But as more states move to restrict abortion, these providers are finding themselves navigating an increasingly complicated legal landscape.

Is abortion by telemedicine legal? Experts differ

Medication abortions work for most people who are under 11 weeks pregnant, and research suggests medication abortion via telemedicine is safe and effective. Yet many states have enacted legislation to ban or limit access to telehealth abortions.

But it’s not always clear what that means for doctors like Case who are physically located in a state with abortion restrictions but have a license that enables them to provide care via telehealth to patients in states where it is legal.

Case says she has consulted several lawyers about the legality, and none of them had a concrete answer for her.

“One lawyer was like, ‘If anyone tells you they think they know [or] they have certainty about this stuff, they’re out of their mind’,” she says.

In many states, patients seeking a telehealth abortion have to be physically present in a state where telemedicine abortion is legal, even if it’s just to have a brief virtual consultation with a provider, who may be located in an entirely different state.

These providers are finding themselves in a murky gray area legally, having to weigh how much risk they’re willing to assume to care for their patients, or consider halting this aspect of care altogether.

Katherine Watson, a law professor and medical ethicist at Northwestern University Feinberg School of Medicine in Chicago, says this is uncharted territory.

“The stakes are so high. We’re talking about something that’s a protected right in one state and a felony in a sister state,” Watson says. “And the map is a patchwork. So this is an absolutely radical change.”

People have to understand the distinction between the letter of the law and the enforcement environment, she says. Even if the law does not explicitly criminalize what doctors like Case do, the enforcement environment can ensnare some of them in legal trouble.

“In a draconian enforcement environment, you may not have violated the letter of the law. But creative prosecutors may look for a reason to persecute you,” Watson says.

There is no slam-dunk argument prosecutors can use, she says, but in a charged political environment, there is a real risk. Look no further than Dr. Caitlin Bernard, an Indiana OB-GYN who spoke out about a legal abortion she provided earlier this summer to a 10-year-old rape victim from Ohio; Bernard was vilified and publicly accused of wrongdoing by the state’s attorney general.

Providers have to weigh the risks

Case works with Whole Woman’s Health, a reproductive health clinic that offers telemedicine abortion in five states: Illinois, Minnesota, New Mexico, Virginia and Maryland. The organization does not have a brick and mortar clinic in some of these places, but it works with providers who have medical licenses there to staff virtual appointments.

Whole Woman’s Health’s president and CEO, Amy Hagstrom Miller, says she speaks with providers about the risks they face working for the clinic. She suspects the lack of clarity in state laws is by design, intended to “scare people away from providing safe abortion care.”

With Indiana’s recent abortion ban now on hold, for now, Case says she is looking into continuing to provide telemedicine abortions. But if the ban takes effect again, she says, she will reluctantly stop those services. The risk is too high.

Farah Yousry/ Side Effects Public Media


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Farah Yousry/ Side Effects Public Media

With Indiana’s recent abortion ban now on hold, for now, Case says she is looking into continuing to provide telemedicine abortions. But if the ban takes effect again, she says, she will reluctantly stop those services. The risk is too high.

Farah Yousry/ Side Effects Public Media

The clinic has already stopped working with providers based in Texas because of the way the abortion law there allows for anyone — even someone not personally affected — to sue anyone who performs, aids or intends to aid in an abortion. That opens the door for political, cultural and even personal grievances to interfere with health care providers’ work.

“Just because you comply with the law doesn’t mean that anti-abortion people won’t come after you and try to vilify you and make your life difficult,” Hagstrom Miller says.

In late August, on one of Case’s days off from her job caring for Indiana patients, she sat at her laptop as one of her cats nestled in her lap quietly and her first telemedicine abortion patient logged on.

The woman was a pregnant student from Texas who was sitting in her car. The camera displayed only the top half of her face. She had driven for hours to New Mexico seeking a prescription for abortion pills.

Case walked her through what to expect, explaining that abortion pills stop the pregnancy from progressing and prompt the body to eject the embryo within a few hours.

“It depends on the person, but many people describe it as a heavy period,” Case told the young woman.

The patient asked for a medical note to excuse her from school, but asked that the note not mention that she’d had an abortion.

It’s women like these who motivate Case to take on telemedicine abortion cases.

With Indiana’s abortion ban now on hold, Case says she is looking into continuing to provide telemedicine abortions. But if the ban takes effect again, she says, she will stop those services. The risk is too high.

If more providers in these states decide the risk is too high, Hagstrom Miller says, the clinic is ready to divert the patient load to providers in states where abortion remains legal and protected.

For her part, Case says, if the patient volume is high enough, she might consider driving over the state border, to neighboring Illinois, so she can continue to provide these telemedicine services.

“I just think it’s a crazy thing to think I will drive 1 1/2 hours to Illinois to use my New Mexico [medical] license to help people driving from Texas to New Mexico to get their abortion,” she says. “It’s just, like, madness.”

This story comes from NPR’s health reporting partnership with Side Effects Public Media, Midwest Newsroom and Kaiser Health News (KHN).

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CBD For Pain Management: Everything You Need to Know

CBD For Pain Management: Everything You Need to Know
CBD For Pain Management: Everything You Need to Know

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Cannabidiol (CBD) can give several health benefits to the human body without the psychoactive effects of its close relative, delta-9-tetrahydrocannabinol (THC). In particular, CBD’s analgesic or painkilling properties have been studied extensively over the past two decades, with encouraging outcomes. Though studies into the efficacy of CBD oil for pain management are still in their infancy, the following are some preliminary findings.

CBD For Pain Relief

There are currently no CBD-based pain medicines available in the United States. Epidiolex, used for uncommon kinds of epilepsy, is the only CBD medication approved by the Food and Drug Administration (FDA).

Meanwhile, CBD’s usage for specific illnesses is legal in some countries. For instance, the U.K. approved it for multiple sclerosis, and Canada did the same for cancer pain. In addition, recent studies have shown promising results for using CBD oil to treat the pain associated with various medical disorders, including arthritis and fibromyalgia.

Interestingly, a recent poll of 2,000 American adults conducted by Forbes Health found that 60% of those who use CBD products do it hoping it may reduce their pain.

So what kind of pain relief does CBD have to offer? Let’s read on to find out.

Chronic Pain Management

There are many reasons why you may develop chronic pain. Common causes include severe injuries, illnesses, and your lifestyle, such as being hunched over an office desk. You can feel this pain anywhere in your body, yet almost eight in every ten Americans experience it in their back. Unlike most conditions, back pain is not easily treatable, often resulting in you taking a concoction of medication to subside it. So CBD for back pain may be a useful alternative for those with chronic pain who are currently taking opioids, which can be habit-forming and have several undesirable side effects.

 Helps with Inflammation

Inflammation is swelling that can lead to joint-related conditions like arthritis. If you’ve experienced pain in your joints, then you’re well aware of how swelling travels fast, causing stiffness and strong jolts of numbness in your limbs. One way to counter this pain is with CBD oil. You can massage the product onto your skin, feel it attack your sore spots, and reduce the swelling around your joints.

According to research carried out in 2018, participants with osteoarthritis-related knee pain used 250 mg to 500 mg of CBD daily on their joints, whereas a separate group used a placebo. When the participants got assessed weekly, those who applied CBD noticed a significant improvement in their condition.

Massaging the CBD oil into your skin will create heat, encouraging your body to react faster to stimulus. Though following the application, you may need to retry a few times before you see promising results, your consistent efforts in using this product will help.

CBD for Neuropathy

Neuropathy is an illness caused by problems with the peripheral nerves. Diabetes, systemic disease, and infection are just a few of the possible triggers of neuropathy.

Most nerve damages lead to muscle fatigue, a sharp pain that radiates everywhere in your body, and numbness. This can cause you to become bedridden or seek emergency care if you don’t feel the pain subside. As a long-term solution taking too many painkillers is not a sustainable option, and there is a massive risk if you opt for surgery.

A 2020 study that investigated the usage of CBD oil on patients with damage to the peripheral nervous system experienced an intense relief after several uses. However, those who used a placebo continued getting harsh and sharp pain which was sometimes unmanageable.

Helps Subside Cancer Treatment Pain

Cancer can take a massive toll on your body from when you get diagnosed to when you begin treatment. The rounds of chemotherapy and radiation can often leave you with unwanted side effects such as nausea, dizziness, a reduced appetite, and fatigue. In some cases, you may also need extra support in the form of high-dosage painkillers like oxycodone and morphine to numb the ache from your radiation spots.

But narcotic analgesics can lead to gastrointestinal problems, constipation, and cognitive issues such as increased drowsiness. This is where CBD comes into play. According to a 2020 peer-reviewed study, CBD can help manage palliative and non-palliative pain in cancer patients.

How To Pick A CBD Product?

It can be difficult to sort through the constantly expanding selection of CBD products and methods of use to find the one that best suits your needs. CBD can be taken orally or applied topically and is available in capsules, oil, tinctures, and other topical treatments.

Every CBD product must have specific labels that disclose both the CBD and THC concentrations, with the latter needing to be below 0.3% under the law. Try to find something that is high in CBD but low in THC. Make sure you know how much CBD is in each bottle or dose, and stay away from anything that doesn’t identify the supplement information and all of the ingredients it contains.

Also, you must determine your intended application of the product. For example, if you are looking for relief from chronic pain, it is best to use a product with a high concentration of CBD. Try taking CBD in capsule or oil form if you’re using it to help with anxiety or depression. You can add CBD oil to your beverage or put a few drops under your tongue.

Final Thoughts

Even if there isn’t solid evidence that cannabidiol (CBD) or CBD oil is superior to other pain treatments, experts agree that it has promising potential. Many patients with chronic pain may find relief with CBD products and won’t get high or become dependent on them, as can be the case with certain medications. However, picking out a CBD product can be a challenge. Consult your physician before using CBD oil for long-term pain. With their assistance, you can find the optimal initial dose and a possible product recommendation.

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How HGH Injections for Sale Will Affect You?

How HGH Injections for Sale Will Affect You?
How HGH Injections for Sale Will Affect You?

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If you are looking for hgh injections for sale, you need to have some knowledge about it first.HGH has been demonstrated to safely and effectively slow down, decrease, or even stop the effects of aging. It was previously only accessible through pricey prescriptions and frequent injections.

How can HGH or HGH injections for sale benefit the body?

  • Reduce body fat.
  • Superior Muscle Tone Without Exercise
  • Loss of weight
  • Your Energy Level Will Rise
  • Cardiovascular Support – Lower Cholesterol
  • Improve Skin Tightness and Reduce Wrinkles
  • Enhance your skin, hair, and nails.
  • Improve your sleep
  • Strengthen sex function
  • Boost Cognitive Function
  • Heighten bone density.
  • Enhance bone density, healing time, cholesterol, immune, and heart health.
  • Boost mental focus, memory, and brain function.

HGH is connected to everything that occurs in your body. HGH is frequently referred to as the “fountain of youth.” Elevated HGH levels are what make you feel young again.

Does your body always produce HGH?

The good news is that your body must always produce HGH for you to survive. The bad news is that your body starts producing less HGH every year beyond roughly the age.

  1. You will likely have lost 75% of the HGH your body produces by the time you turn 60.

Do HGH Injections Help? The Truth Is Out

With the vast majority of men and women attempting to battle and combat age effects,

anti-aging treatments are increasingly popular. HGH has gained popularity recently due to its propensity to keep you young. It is one of the main reasons people are looking for hgh injections for sale. Growth hormone is available in many forms, and injections are one of them. But do they assist?

Are HGH injections for sale helpful?

HGH injections are, without a doubt, the most efficient kind of growth hormone and deliver quick results. These shots are a replacement therapy that injects the body with human growth hormone obtained from the donor’s post-mortem pituitary.

These shots interfere significantly with your body’s internal mechanisms because they are not a natural process. As a result, it is likely to have a lot of unfavorable impacts. For instance, the following are some of the side effects of such therapy:

  • Hypertension
  • Soft tissue enlargement
  • Muscular tremor
  • Elevated diabetes risk

If your pituitary gland shuts down due to colon, lung, or breast cancer, this can cause an overabundance of growth hormones to circulate in your blood.

Once you stop getting these shots, you’ll likely age more quickly.

Additionally, these images end up being very pricey. A single injection can cost $25; if you need three days, your costs could reach $75 per day. As a result, these shots will probably cost a lot for both your cash and body.

A better and safer alternative to injections is growth hormone releaser pills or supplements. These dietary supplements operate as simulators, causing your pituitary gland to produce and secrete more growth hormone so that you may use your glandular system to absorb it exactly as you did when you were younger.

These pills offer a comprehensive body makeover with no adverse effects.

Despite the abundance of supplements, you must pick one carefully. Make sure the supplement you purchase has received clinical approval and physician endorsement. Additionally, you must confirm that it was produced in a GMP-certified lab, as this guarantees great quality.

HGH Spray for Rejuvenation

Do you want to feel and look younger? So, have you thought about trying a product that fights aging and rejuvenation? The consequences of aging by 10 to 20 years can now be reversed, according to Dr. Klatz. Injections of the human growth hormone (HGH), which has remarkable health advantages, are the subject of this claim. Injections of HGH have been around for a while. However, the expense and related adverse effects of HGH injections have severely limited their use since they were initially utilized. All that changed with HGH spray. The invention of HGH spray has made the incredible advantages of HGH accessible to the general population and everyone who needs it.

HGH injections for sale or HGH spray have remarkable anti-aging effects, particularly in those who lack the hormone. Due to a decrease in HGH production as we age, adults often have insufficient hormone levels. When we are young, HGH is created in large quantities, but as we age, this production decreases. By the time we reach the age of 60, many of us will only have 25% of our hormone levels from when we were 20. More than 20,000 studies conducted over the years have shown that replenishing the body with the missing hormone can restore young radiance and vigor.

Studies demonstrate that aged subjects who use HGH supplements become more youthful.

HGH Is Safe and Simple to Use

HGH is first exclusively administered intravenously. But only the rich and famous can get injections because of their hefty cost. Furthermore, HGH injections have been associated with several adverse consequences, including bone distortion and overgrowth. The demand for HGH supplements is still very high. As a result, producers are under pressure to create an injectable substitute that is both affordable and efficient. There are currently many HGH products on the market. These goods don’t have artificial HGH in them. Instead, they are filled with the components needed to make HGH. Amino acids and alpha GPC are examples of these substances referred to as stimulators. Since HGH is a protein, amino acids are necessary for its synthesis.

Choose an HGH spray if you want assurance that the effects of HGH will be felt. The most practical, economical, and secure alternative to HGH injections for sale. HGH spray directly provides vital components into the bloodstream through the mouth cavity. Studies show that spraying is the most efficient way to get HGH into the body. This guarantees HGH’s anti-aging and regenerative properties. The hormone can be increased more effectively by promoting the natural synthesis of the hormone. Increasing HGH levels is essentially a health and beauty fad, but you should always choose the less risky, more affordable, and more dependable option, like HGH sprays.

Therefore, get a good provider and dependable source for HGH injections.

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history of genetic testing?How are genetic diseases detected?

history of genetic testing?How are genetic diseases detected?
history of genetic testing?How are genetic diseases detected?

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Contributed by: Anjali Dharra

What is the family history/pedigree analysis?

Family history, or pedigree analysis, is an important record of the health conditions/inherited diseases of a person and his/her close relatives. The complete record of a family’s history incorporates health information from three generations of relatives. These three generations include:

  • Children
  • Brothers and sisters
  • Parents
  • Grandparents 
  • Aunts and uncles
  • Nieces and nephews
  • Cousins

Families tend to have a similar genetic background and most often have the same environmental and lifestyle behaviours. These factors together give clues to health conditions that may run in families. Genetic testing provides complete information about a family’s history and the causes of ongoing health conditions and the risks of acquiring new ones. 

By identifying the patterns or health disorders among relatives, expert healthcare professionals can easily determine whether this health condition persists in generations or not, just by looking at the genetic testing report in which multiple genes have been detected and identified to find out the genetic predisposition for health abnormalities and diseases. 

Family history can identify people with a higher than usual risk of many common lifestyle illnesses or disorders, such as high blood pressure, heart disease, stroke, type 2 diabetes, and certain cancers, to name a few. These disorders can be easily influenced by a combination of genetic factors, lifestyle changes, and environmental behaviours. 

In addition to this, family history can also tell about the rare health conditions that are most often triggered by a mutation in genes, namely cystic fibrosis and sickle cell anaemia.

Questions asked by the doctor while studying a family’s history:

Here is a list of questions that are frequently asked by healthcare professionals before recommending genetic testing or prediction of health conditions. These include:

  1. How old you are?
  2. Do you or any of your family members/relatives have/had any long-term mild or chronic health disorders?
  3. How old are they, when they were diagnosed?
  4. Are/were their illnesses under control?
  5. How are/were they treated?
  6. Where do/did they come from/belong to?
  7. Did your late relatives have health problems and what were those problems?
  8. How old were they when they died?
  9. What were the reasons for their deaths?

Answers to all these questions aid healthcare professionals to:

  • Assess the health risks based on your family history and other environmental factors.
  • Recommend healthy diets and lifestyle changes to prevent or treat the diseases.
  • Suggest health screening tests to diagnose the disease at the earliest.

What if you do not uncover your family’s history?

Being aware of the family health history is an important aspect that plays a vital role in adapting a lifelong wellness plan. It might be a possibility that no one in your family or relatives has any past health history or genetic disorders, but you still may have at risk of developing a health disease. This is because of the following reasons:

  • Diet and nutrition
  • Lifestyle behaviours
  • Personal medical history
  • Other environmental factors
  • Being unaware of any family member’s health history
  • Might have family members who died young before developing a health condition into chronic or severe stages such as cardiac diseases, diabetes, cancer, and stroke, to name a few.

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Does delta-8 THC help with anxiety?

Does delta-8 THC help with anxiety?
Does delta-8 THC help with anxiety?

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Delta-8 THC is a type of cannabis with a lower level of psychoactive properties than other types of cannabis. Delta-8 THC is most commonly found in products like vape oils and tinctures.Delta-8 THC is not as psychoactive as different types of cannabis, so it is less likely to cause intoxication. It is also less potent, so you need to use smaller doses to achieve the same effect.

Some people use delta-8 THC to treat conditions like chronic pain, anxiety, and depression. It effectively treats those conditions and does not have the same side effects as other cannabis products.

Uses of Delta-8 THC

Delta-8 THC is a nonpsychoactive cannabinoid found in industrial hemp oil. It has been used to treat various medical conditions for centuries.

Today, Delta-8 THC is used as a therapeutic agent to improve the symptoms of various medical conditions. These include:

  1. Neurodegenerative diseases, such as Alzheimer’s and Parkinson’s diseases
  2. Epilepsy
  3. Autism Spectrum Disorder (ASD)
  4. Anxiety and stress disorders
  5. Cancer treatment side effects
  6. Sleep disorders
  7.  HIV/Aids treatment side effects
  8. Post-traumatic stress disorder (PTSD)

If you’re looking for an alternative to THC distillate, THC-O distillate may be a good option. THC-O distillate is made from cannabis flowers that have been steam distilled. This process removes most of the plant’s cannabinoids, leaving behind only the terpenes. This makes THC-O distillate a more concentrated form of cannabis than THC distillate. It can also be used in place of THC distillate in many recipes.

Delta-8 THC help to cope with anxiety

Delta-8 THC is a type of cannabis that has been shown to help with anxiety and other conditions. It interacts with the body differently than other cannabinoids, which may make it more effective.

Some believe delta-8 THC is the most effective cannabinoid for treating anxiety and other conditions. It interacts with the body differently than other cannabinoids, which may make it more effective.

There are many different brands of delta-8 THC products available on the market today. You can find them in dispensaries, online, or in specialized health stores.

If you are interested in using delta-8 THC to treat your anxiety, speak to your doctor first. They will be able to advise you on how much delta-8 THC to use and when to use it.

The Best Ways to Use Delta 8 THC

1) Tinctures

Delta THC tinctures are a great way to use Delta THC. They are easy to take and can be used in various ways. One of the best ways to use Delta THC is by using tinctures. Tinctures are easy to take and can be used in various ways. You can take them orally, apply them topically, or vape them. They are also a great option for people who want to avoid smoking or vaping cannabis. Tinctures are also a great way to save money. They are affordable and can last for a long time. Plus, they don’t require any special storage or preparation. Simply add Delta THC tincture to your desired beverage or food, and enjoy!

2) Edibles

One of the best ways to use Delta THC is through edible products. Edibles are a great way to enjoy Delta THC’s benefits without worrying about the psychoactive effects. Delta THC can be found in many forms, including capsules, tinctures, and edibles. Each form has its unique benefits and drawbacks.

Capsules are the most common form of Delta THC and are easy to take on the go. However, they often have a strong smell and taste, which some users find unpleasant. THC Lean is also easy to take. They tend to have a more mellow effect than capsules and are less likely to cause nausea or vomiting.

Edibles are the best option for those who want to enjoy the full psychoactive effects of Delta THC. They often have a sweet or sour taste and provide a longer-lasting high than other forms of Delta THC. However, edibles are also the most dangerous way to consume Delta THC. It is important to know your dosage and ensure you don’t overdo it.

3) Vaping

One of the best ways to use Delta THC is to vape it. Vaping allows you to inhale the cannabinoids quickly and easily. Vaporizing also allows you to control your dose, which is essential for people new to cannabis.

Delta THC can also be smoked. This is the most common way people consume marijuana and is the most traditional. Smoking Delta THC allows you to enjoy the flavor and smell of cannabis. It also gives you a quick hit of cannabinoids.

4) Smoking

Delta THC can be used in various ways, but one of the best ways to use it is to smoke it. Smoking Delta THC allows you to enjoy the drug’s benefits without worrying about the smell or other unpleasant side effects.

Smoking Delta THC also lets you take advantage of its psychoactive properties. This means that you can experience the effects of the drug immediately. This is a handy feature if you want to get high quickly.

 

 

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7 Things You Must Know About Diet Supplements

7 Things You Must Know About Diet Supplements
7 Things You Must Know About Diet Supplements

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Many people use dietary supplements to help them get and stay healthy. One type of dietary supplement is herbal medicines or botanicals, also known as “natural products.” Dietary supplements are widely available in pills, powders, or liquids. While there is plenty of evidence that dietary supplements can help prevent and treat nutrient deficiency, there is much less evidence that they can help prevent or treat other diseases. As a result, there is a lot we do not know.

Here are seven things to consider if you are considering or using a dietary supplement.

Take control of your health by becoming a well-informed consumer. 

The standards for marketing supplements differ greatly from those for drugs. For example, supplement marketers are not required to demonstrate to the Food and Drug Administration that their product is safe or effective before it is placed on grocery store shelves. Learn what the scientific evidence says about the safety and efficacy of a dietary supplement. The resources listed below can assist you.

Natural does not always imply safe.

The herbs comfrey and kava can cause severe liver damage. Furthermore, the term “standardized” (or “verified” or “certified”) on a bottle does not guarantee product quality or consistency.

Interactions may occur

Some dietary supplements may interact with medications (prescription or OTC) or other dietary supplements, and others may have side effects on their own. St. John’s wort interacts with many medications in ways that can interfere with their intended effects, including antidepressants, birth control pills, antiretrovirals used to treat HIV infection, and others, according to research.

Be aware of the possibility of contamination. 

Some supplements have been discovered to contain hidden prescription drugs or other compounds, particularly those marketed for weight loss, sexual health (including erectile dysfunction), athletic performance, or body-building.

Consult your healthcare providers. 

Inform your doctors about any complementary health products or practices you use, such as dietary supplements. This gives them a complete picture of what you are doing to manage your health and ensures coordinated and safe care.

You do not urinate supplements, believe it or not.

One of the most common complaints Firisin receives is about “peeing out vitamins.” While certain supplements can cause your urine to turn yellow and even smell unpleasant, this does not mean you are releasing the excess instead; each nutrient has a specific dosing regimen that is either a basic level for optimal health or a therapeutic level that may be required to achieve a specific goal.

Get specific instead of taking a multivitamin.

We are sorry to break it to you, but if you are still taking it. You need to upgrade if you have gummy daily vitamins from when you were a kid. According to nutritionist Jonny Bowden, Ph.D., CNS, a multivitamin is insufficient for most adults to reap the benefits of supplement use.

Conclusion 

Before taking diet supplements, make sure you go through this article so it can help you be on the right track in your new journey. With this information, you can get the most effective diet supplement.

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6 Benefits and Uses of CBD Oil

6 Benefits and Uses of CBD Oil
6 Benefits and Uses of CBD Oil

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Constant headaches, illnesses, sore muscles… as if the stress of everyday life wasn’t enough. We all wish there were a panacea for all our aches and pains, but we still have to look for alternatives to miracle solutions.

Different companies are offering us various supplements and cosmetics formulated to make our daily lives easier and to help our appearance hide signs of aging and exhaustion. There may not be any magical potion on the market yet, but we can make good use of trying out the accessible novelties.

Now, it might be about time to take a closer look at the benefits of using CBD oil. After all, there are more and more companies perfecting CBD products for the growing number of customers, and it is only natural to be curious about the reasons “why.” Read on to learn more about how this natural substance can benefit you!

Here Are The Six Benefits and Uses of CBD Oil

CBD Calms you Down

The calming effect is as broad as it sounds. CBD is helpful in dealing with daily stress and can also be used as a form of support by people dealing with anxiety. It can be added to tea, coffee, or consumed in the form of CBD edibles, among other consumption methods.

People experiencing stress and anxiety should consider full-spectrum CBD products. You don’t need to worry about the intoxicating effects of THC, which can be found in the full-spectrum CBD oil, as it contains only trace levels of the substance (legally no more than 0.3%). CBD has a similar chemical structure to THC but is devoid of its intoxicating properties.

CBD Relieves Pain

CBD oil is mostly associated with pain relief. CBD interacts with the body’s endocannabinoid system (ECS), which is responsible for maintaining certain aspects of our health, including sleep, appetite, and pain response.

For instance, products containing broad-spectrum hemp CBD oil, such as salves, balms, or oil in a bottle with a dropper applicator, are popular among people dealing with pain or inflammation and the side effects of intense physical activity or injuries.

These products can be easily applied directly to the affected area or, in the case of the oil, consumed sublingually.

CBD Reduces Acne

There were times when steroid ointments were on top of the acne treatment methods. Unfortunately, they were often very harsh on the skin and caused irritation or even pain. Now cosmetology has new solutions, and CBD oil cosmetics are among them.

The anti-inflammatory properties of CBD reduce skin irritancy. Besides that, CBD regulates sebum production and heals scars. To reduce acne, you might want to reach for either a pure CBD oil (CBD isolate) or natural cream containing it.

CBD Manages Appetite

The endocannabinoid system is responsible for many different processes in our bodies. One of them is appetite regulation. When this system is not working properly, we may experience sudden hunger attacks or, on the contrary, a loss of appetite.

CBD oil is sometimes used as a means to control appetite. The effect is not as strong as that of pharmaceutical drugs but is much safer and does not lead to addiction.

However, if you’re already talking about other supplements or medications, you should consult a doctor before including CBD in your daily routine.

CBD Supports Recovery After Workout

The benefits of CBD oils are increasingly more popular in the sports environment. After a day of hiking or an intense jogging session, your joints and muscles are tired and tense. Stretching exercises and hot showers sometimes are not enough.

Before going for traditional painkillers, try to complement your usual after-workout ritual with CBD oil balms. The anti-inflammatory properties of CBD will quicken the recovery and soothe the pain of possible injuries.

CBD Is Good for Your Pets

We’re not trying to talk you into getting your puppy high. However, the calming CBD properties can also benefit your furry best friend. There are specially formulated CBD oils and treats that can be used to help your dog or cat that struggles with anxiety or pain.

CBD animal products are available in various forms, such as oils, powders, capsules, or even dog biscuits. It is advisable to start with smaller doses and observe your pet’s reaction before increasing the amount. Also, talk to your vet first.

In Conclusion

There are many reasons why you should look into using CBD oil for the health issues you’re experiencing. It is a natural substance that can help improve your overall health and is unlikely to cause side effects.

Remember that you should always consult your doctor before trying out any new remedy or supplement. This is especially important if you have a serious illness or take other medications!

Also, remember that CBD oil will not provide you with immediate relief from your problems and that it takes time to yield results. This is why it is essential to set realistic expectations before using CBD oil and stick to your plan.

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